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Atlético San Luis vs León Prediction: Match Preview and Analysis | Liga MX 22-03-2026

Atlético San Luis

1 - 2

FT

León

Estadio Alfonso Lastras Ramírez
Luis Enrique Santander Aguirre
sky is clear 14.52 °C

Prediction published on Mar 21, 2026 12:34 AM by Dario in Mexico - Liga MX | Modified on Mar 21, 2026 12:34 AM

The twelfth round of the Liga MX continues with an intriguing clash between Atlético San Luis and León, two sides in need of a positive result to revive their campaigns. The match will take place at the Estadio Alfonso Lastras, where both teams aim to show character and move closer to the upper half of the table. Despite their struggles, this fixture promises intensity, as both clubs are desperate to end their inconsistent runs.


Atlético San Luis: Searching for Stability at Home


Atlético San Luis arrive at this encounter sitting 12th in the Liga MX standings. Their record of three wins, two draws and six defeats has left them with 11 points, 17 goals scored and 19 conceded. The team’s recent form has been irregular, with only one victory in their last five matches (one win, one draw, three losses). Their latest outing was a 1-1 draw against Pachuca, following a heavy 3-0 defeat to Cruz Azul and a convincing 4-1 win over Mazatlán.


Throughout the current season, San Luis have shown a tendency to produce open games, averaging 1.5 goals scored and 1.7 conceded per match. They have also been involved in matches with plenty of second-half action, as over 0.5 goals have been scored after the break in each of their last 15 league games. However, consistency remains their biggest challenge — they have failed to draw in 37 of their last 40 Liga MX fixtures, a sign of their unpredictable nature.


One of the standout performers for the home side is Joao Pedro, the 34-year-old Italian forward who has already netted 10 goals this season. His scoring instinct and leadership up front make him a key figure in San Luis’s attacking setup. Last season, he shared the top scorer title with 17 goals and continues to be the main offensive reference for the team.


León: Struggling to Find Direction


León come into this match in a difficult situation, sitting 16th in the table with three wins, one draw and seven defeats. Their defensive fragility has been a major issue, with 23 goals conceded so far, compared to only 11 scored. The team’s last five matches have produced two wins and three losses, but their most recent results have been worrying — including a heavy 5-0 defeat against Guadalajara on March 19.


León’s season statistics underline their struggles: an average of 0.9 goals scored and 1.9 conceded per game. They have allowed at least one goal in each of their last 20 league matches, showing how difficult it has been to maintain defensive solidity. Away from home, their record is even more concerning — they have failed to win in 19 of their last 20 away games and have lost at half time in each of their last four away fixtures.


Despite these numbers, León still possess individual quality. Midfielder José Rodríguez has been one of the few bright spots, starting seven of ten matches and averaging 62 minutes per appearance. However, the team’s lack of a permanent coach after the departure of Ignacio Ambriz has left them without clear direction, and they urgently need to rediscover confidence to avoid sinking further down the table.


Atlético San Luis vs León: Tactical Overview and Key Factors


This encounter brings together two teams with contrasting strengths and weaknesses. Atlético San Luis tend to perform better at home, where they can rely on their supporters to push them forward. Their attacking play, led by Joao Pedro, has been effective when given space, but defensive lapses have cost them valuable points. On the other hand, León are struggling to find balance between attack and defense, often conceding early and failing to recover.


Historically, the head-to-head record slightly favors León, with three wins compared to two for San Luis in their last five meetings. The most recent clash ended 0-1 in July 2025. However, given the current form of both sides, this match could be more open than previous encounters. The statistics suggest a high probability of goals, as over 1.5 goals have been scored in 19 of León’s last 20 matches, while San Luis also tend to produce goal-filled games.



  • Atlético San Luis average goals per match: 1.5 scored, 1.7 conceded.

  • León average goals per match: 0.9 scored, 1.9 conceded.

  • Both teams have scored in 57% of their recent matches.

  • Over 2.5 goals have been recorded in 57% of their combined fixtures.


Given these trends, fans can expect an entertaining contest with opportunities at both ends. San Luis will look to exploit León’s defensive weaknesses, while the visitors will aim to counterattack and take advantage of any mistakes from the hosts. The outcome may depend on which side can maintain composure in key moments.


BetMines Prediction


According to the latest data, the most likely scenario for this Liga MX clash is Both Teams To Score – Yes, with a probability of 57%. Both sides have shown defensive vulnerabilities but possess enough attacking quality to find the net. Expect an open and competitive match where goals on both ends seem the most probable outcome.

Atlético San Luis vs León - Predictions

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Atlético San Luis vs León: Pre-match Stats Comparison

This section provides average statistics and percentages on the main markets for the last 10 matches of both teams

Atlético San Luis

León

Under

Over

Under

Over

0.5

0%

0

100%

10

0%

0

100%

10

1.5

10%

1

90%

9

10%

1

90%

9

2.5

50%

5

50%

5

20%

2

80%

8

3.5

80%

8

20%

2

60%

6

40%

4

4.5

80%

8

20%

2

70%

7

30%

3

BetMines

Standings of Atlético San Luis and León in Liga MX

Who will win ?

Atlético San Luis vs León: Frequently asked questions

Can’t find the anwser you’re looking for ? Reach out to customer support team.
When will Atlético San Luis vs León be played?
The Liga MX match between Atlético San Luis and León will be played on March 22, 2026 at 01:00.
Where will Atlético San Luis vs León be played?
The match between Atlético San Luis and León will be played at Estadio Alfonso Lastras Ramírez, San Luis de Potosi - Mexico
Who will referee Atlético San Luis vs León?
The referee for the match will be Luis Enrique Santander Aguirre.
What are the 1X2 betting odds for Atlético San Luis vs León in the Liga MX?
The odds are: Atlético San Luis to win 2.15, draw 3.70, León to win 3.20.
What are the betting odds for Atlético San Luis vs León for Over/Under 2.5 goals in the Liga MX?
The odds are Over 2.5 at 1.66 and Under 2.5 at 2.15.
Will both Atlético San Luis and León score in the Liga MX?
The odds for both teams to score are 1.57, while the odds for at least one team not to score are 2.25.
What is the most likely correct score for Atlético San Luis vs León in the Liga MX?
The most likely correct score is 1-1, with odds of 7.
What are the head-to-head results between Atlético San Luis and León?
In the last 5 head-to-head matches between Atlético San Luis and León, Atlético San Luis won 2 times, León won 3, and 0 ended in a draw.

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