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Prediction published on Mar 9, 2026 6:01 PM by Dario in Europe - Champions League | Modified on Mar 9, 2026 6:01 PM
The UEFA Champions League knockout stage continues with an exciting clash between Bayer 04 Leverkusen and Arsenal. The first leg of this last-16 tie promises intensity and high-quality football as the German side look to stop the English giants’ impressive run. Arsenal arrive in top form, unbeaten in the competition so far, while Leverkusen will rely on their home support to gain an advantage before the return leg in London.
Bayer 04 Leverkusen enter this encounter after a 3-3 draw against SC Freiburg on March 7, a result that extended their mixed run of form. Over their last five matches, they have recorded one win, three draws, and one defeat, averaging 1.0 goal scored and 1.0 conceded per game. In the Champions League, their record stands at four wins, four draws, and two losses, with an average of 1.5 goals scored and 1.4 conceded per match. These numbers underline a team that can compete but often struggles to maintain consistency against top-level opposition.
Leverkusen’s home performances in Europe have been unpredictable. They have managed only one victory in five home games this season, a 3-0 success over Villarreal, while suffering a heavy 7-2 defeat to PSG earlier in the campaign. Despite that setback, the German side have shown resilience, remaining unbeaten in their last six home fixtures across all competitions, though the last two ended in draws. Their defensive line has improved recently, keeping several clean sheets before conceding against Mainz, but facing Arsenal’s attack will be a much tougher challenge.
Injuries could also play a role in this tie. Key striker Patrick Schick remains doubtful, while other players such as Mark Flekken, Loic Bade, and Arthur are also uncertain. The team will look to maintain their defensive discipline and capitalize on counterattacks, hoping to secure a positive result before traveling to England.
Arsenal come into this match in outstanding form, having won 1-2 against Mansfield Town on March 7. Over their last five matches, they have collected four wins and one draw, scoring an average of 2.2 goals per game while conceding just 1.0. Their Champions League campaign has been flawless so far: eight wins from eight matches, with 23 goals scored and only four conceded. The Gunners’ attacking efficiency and defensive solidity make them one of the most balanced teams in the competition.
Arsenal’s away record in Europe is particularly impressive. They have won all four of their away games in this season’s Champions League, with a combined score of 11-1. The team has not lost in 20 of their last 21 away matches and has scored in 20 of those. They have also been dominant in first halves, winning at half time in seven of their last ten away fixtures. These statistics highlight a side that starts strong and maintains control throughout the match.
In addition to their European success, Arsenal are performing well domestically, sitting at the top of the English Premier League and competing in multiple cup competitions. Although there are some injury concerns — with William Saliba, Martin Odegaard, and Ben White listed as doubts — the squad depth remains strong. Eberechi Eze’s recent form provides an extra attacking option, while the return of Piero Hincapie, on loan from Leverkusen, adds an interesting subplot to this encounter.
This matchup brings together two teams with contrasting trajectories. Bayer Leverkusen have shown flashes of quality but lack the consistency needed to challenge Europe’s elite. Their defensive structure will be tested against an Arsenal side that has scored in every Champions League match this season. The Gunners’ ability to dominate possession and create chances from wide areas could prove decisive, especially given Leverkusen’s vulnerability when pressed high.
Historically, Arsenal have the upper hand in this fixture, winning their last meeting 4-1 back in 2002. While that result is long in the past, the current form suggests a similar pattern could emerge. Leverkusen’s best hope lies in exploiting set pieces and quick transitions, but Arsenal’s defensive organization and attacking rhythm make them clear favorites. The English side’s unbeaten run in the competition and their record of winning at half time in recent matches further strengthen their case.
Given the data and recent performances, Arsenal appear well-positioned to extend their winning streak in Europe. Leverkusen’s home advantage might help them stay competitive early on, but sustaining that level for 90 minutes against such an efficient opponent will be difficult.
Bayer 04 Leverkusen vs Arsenal prediction by BetMines:
Arsenal win (2) with 44% probability.
This section provides average statistics and percentages on the main markets for the last 10 matches of both teams
Bayer 04 Leverkusen
Arsenal
Under
Over
Under
Over
0.5
0
10
1
9
1.5
1
9
5
5
2.5
4
6
6
4
3.5
6
4
10
0
4.5
7
3
10
0