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Prediction published on Mar 21, 2026 12:49 AM by Dario in Brazil - Serie A | Modified on Mar 21, 2026 12:49 AM
The upcoming clash between Cruzeiro and Santos promises to be one of the most intriguing fixtures of the Brasileirão Série A weekend. Scheduled for Sunday, March 22, 2026, this match brings together two traditional clubs that are currently struggling to find consistency in the early stages of the season. Both sides have recently changed their managers, hoping to reverse a series of disappointing results and regain momentum in the league.
Cruzeiro enter this encounter in a delicate position, sitting 19th in the Serie A standings. The team’s recent form has been far from ideal, with no wins in their last five matches — three draws and two defeats — and an average of 1.4 goals scored against 2.0 conceded per game. Their most recent outing ended in a 2-1 loss to Athletico PR on March 18, 2026, further highlighting the defensive issues that have plagued them since the start of the campaign.
Across the season, Cruzeiro’s record stands at 0 wins, 3 draws, and 4 losses, with an average of 1.1 goals scored and 2.3 conceded per match. Despite these struggles, the team tends to start games strongly at home, having led at half time in six of their last ten home fixtures in Serie A. However, defensive lapses have often undone their early efforts, as they have conceded at least one goal in each of their last twelve league matches.
These numbers suggest that while Cruzeiro are capable of finding the net, their backline remains a major concern. Playing at home could be an advantage, especially given their tendency to start well, but they will need to maintain focus for the full 90 minutes to secure a much-needed victory.
Santos arrive in Belo Horizonte with slightly better numbers but still far from their historical standards. The team currently occupies 16th place in the Serie A table, having collected one win, three draws, and three defeats so far. Their latest match ended in a 2-1 loss to Internacional on March 19, 2026, a result that exposed some defensive vulnerabilities despite a decent attacking display.
In their last five matches, Santos have recorded one win, two draws, and two defeats, averaging 1.4 goals scored and 1.6 conceded per game. The team’s offensive consistency is notable — they have scored in each of their last 14 league matches — but their defense continues to leak goals, particularly away from home. In fact, Santos have lost at half time in nine of their last fourteen away games, a trend that could prove costly against a Cruzeiro side eager to take early control.
While their attack remains productive, Santos’s defensive instability on the road has been a recurring issue. The team will need to tighten up at the back if they are to avoid another setback against a Cruzeiro side desperate for points.
This fixture brings together two teams with contrasting needs but similar weaknesses. Cruzeiro are under pressure to secure their first win of the season and climb out of the relegation zone, while Santos aim to stabilize their campaign and avoid slipping further down the table. Both sides have shown attacking potential but remain fragile defensively, which could lead to an open and entertaining contest.
Historically, recent meetings between these teams have been balanced, with Cruzeiro winning two and Santos three of their last five encounters. The most recent head-to-head ended 3-0 in favor of Cruzeiro on December 7, 2025, a result that the home fans will hope to see repeated. Given the current form and statistical trends, goals are likely on both sides, but Cruzeiro’s home advantage and stronger first-half performances could tilt the balance in their favor.
Expect a match where both teams create chances, with Cruzeiro pushing forward early and Santos relying on counterattacks. The defensive frailties of both sides suggest that the game could feature multiple goals, possibly with both teams finding the net before the final whistle.
Cruzeiro vs Santos prediction from BetMines: Home Win (1) with 56% probability.
This section provides average statistics and percentages on the main markets for the last 10 matches of both teams
Cruzeiro
Santos
Under
Over
Under
Over
0.5
1
9
0
10
1.5
4
6
0
10
2.5
6
4
5
5
3.5
8
2
7
3
4.5
10
0
9
1