The Brazilian Serie A continues with one of its most traditional derbies as Palmeiras host Santos on Thursday, November 6, 2025, at 21:30. This clash brings together two clubs living very different realities: the reigning title contenders from São Paulo face a Santos side struggling to stay clear of the relegation zone. Despite the historical rivalry, the current gap in form and quality between the two teams is significant, making this encounter a real test of resilience for the visitors.

Palmeiras’ Recent Form and Key Stats

Palmeiras approach this match as one of the strongest teams in the country, sitting comfortably at the top of the Serie A table. Their season record of 20 wins, 5 draws, and 5 defeats underlines their consistency and dominance. The team averages 1.8 goals scored and 0.9 conceded per game, showing a balanced mix of attacking efficiency and defensive solidity. In their most recent outing, they defeated Juventude 0-2 away, further consolidating their position as title favorites.

At home, Palmeiras have been almost unbeatable. They are on a remarkable run of 10 consecutive home victories in Serie A and have not lost at half time in their last 13 home matches. The Estádio Allianz Parque has become a fortress where opponents rarely leave with points. In their last five matches overall, Palmeiras have recorded 2 wins, 1 draw, and 2 defeats, scoring an average of 1.6 goals per game while conceding 1.2.

Coach Abel Ferreira faces some selection challenges for this fixture. Paulinho and Lucas Evangelista are sidelined with injuries, while Aníbal Moreno is suspended. There are also doubts over Raphael Veiga and Weverton. Even so, the squad depth remains impressive, with potential starters such as Carlos Miguel, Khellven, Gustavo Gómez, Murilo, Piquerez, Emiliano Martínez, Andreas Pereira, Allan, Mauricio, Flaco López, and Vitor Roque. The attacking options available ensure that Palmeiras can maintain their high tempo and offensive threat even with key absences.

Santos’ Recent Form and Key Stats

Santos arrive in São Paulo under pressure, sitting 16th in the Serie A standings and fighting to avoid relegation. Their campaign so far has been inconsistent, with a record of 8 wins, 9 draws, and 13 defeats. The team averages 1.0 goal scored and 1.4 conceded per match, reflecting their struggles at both ends of the pitch. In their latest match, they drew 1-1 against Fortaleza, a result that extended their winless run and left them still searching for momentum.

In their last five matches, Santos have managed just 1 win, 2 draws, and 2 defeats, scoring an average of 1.2 goals while conceding 1.6. Away from home, their form has been particularly worrying. They have lost at half time in their last three away games and have struggled to impose themselves against stronger opponents. The team’s defensive lapses and lack of creativity in attack have been major concerns for coach Juan Pablo Vojvoda.

The visitors will be without Mayke due to injury and Luan Peres through suspension. Even so, Vojvoda can rely on players such as Gabriel Brazão, Igor Vinícius, Alexis Duarte, Adonis Frías, Escobar, João Schimdt, Zé Rafael, Victor Hugo, Rollheiser, Barreal, and Lautaro Díaz. The challenge for Santos will be to stay compact defensively and exploit counterattacking opportunities, though their recent performances suggest that even scoring could be difficult against Palmeiras’ disciplined back line.

Palmeiras vs Santos Prediction and Tactical Overview

This Paulista derby brings together two clubs with contrasting ambitions. Palmeiras are chasing another league title, while Santos are battling to avoid relegation. The home side’s superior form, squad depth, and tactical organization make them clear favorites. Historically, Palmeiras have also had the upper hand in recent meetings, winning three of the last five head-to-heads and averaging 1.4 goals scored per match against Santos.

Given the current dynamics, Palmeiras are expected to dominate possession and dictate the tempo from the start. Their attacking trio, supported by creative midfielders like Andreas Pereira and Mauricio, should be able to break down Santos’ defense early. The visitors, on the other hand, will likely adopt a cautious approach, focusing on containment and hoping to capitalize on rare counterattacks. However, their recent record of three consecutive first-half losses in Serie A suggests they may struggle to keep the game balanced before the break.

With Palmeiras’ impressive home streak and Santos’ ongoing difficulties away from home, this match could follow a familiar pattern: the hosts taking control early and maintaining their advantage through to the final whistle. A low-scoring encounter is possible, especially considering Palmeiras’ busy schedule and the visitors’ limited attacking output. A 2-0 home win appears a realistic outcome, reflecting both teams’ current trajectories.

Probable Lineups Palmeiras vs Santos

PALMEIRAS (4-2-3-1): Carlos Miguel; Khellven, Gustavo Gómez, Murilo, Piquerez; Emiliano Martínez, Allan; Andreas Pereira, Mauricio, Flaco López; Vitor Roque. Coach: Abel Ferreira

SANTOS (4-3-3): Gabriel Brazão; Igor Vinícius, Alexis Duarte, Adonis Frías, Escobar; João Schimdt, Zé Rafael, Victor Hugo; Rollheiser, Barreal, Lautaro Díaz. Coach: Juan Pablo Vojvoda

Palmeiras vs Santos prediction by BetMines:
The most likely outcome is a Palmeiras win (1) with a 66% probability. The Draw (X) follows at 22%, while a Santos win (2) stands at 12%.