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Prediction published on Dec 28, 2025 11:01 AM by Dario in Italy - Serie A | Modified on Dec 28, 2025 11:01 AM
The Serie A calendar closes its 17th round with an intriguing clash at the Stadio Olimpico, where Roma host Genoa on Monday, December 29, 2025. The match kicks off at 20:45 and promises to be a key moment for both sides — one fighting to stay in the top four race, the other looking to move further away from the relegation zone. Roma come into this fixture after a narrow 2-1 defeat against Juventus before Christmas, while Genoa also suffered a setback, losing 0-1 to Atalanta.
Roma have experienced a dip in form after a strong start to the campaign. Once leading the Serie A standings, three defeats in their last four league matches have seen them slip to fifth place. Despite this, their defensive record remains impressive — they still boast the best defense in the league, conceding only 10 goals so far.
At home, the Giallorossi have been particularly solid, winning four of their last five matches across all competitions. Their consistency at the Stadio Olimpico has been built on a disciplined back line and an ability to grind out results even when not at their attacking best. The team’s recent record shows 10 wins and 6 losses in Serie A, with an average of 1.1 goals scored and just 0.6 conceded per game.
In attack, the return of Artem Dovbyk is a major boost. The Ukrainian striker leads Roma’s scoring charts in 2025 with 15 goals, while other forwards like Paulo Dybala and Evan Ferguson have struggled for consistency. However, injuries and absences could still affect the lineup: Lorenzo Pellegrini is sidelined with a muscle injury, and both Neil El Aynaoui and Evan Ndicka are away on international duty.
Genoa arrive in Rome sitting 17th in the Serie A table, just two points above the relegation zone. Their recent form has been inconsistent, with two wins and three defeats in their last five matches. The team has scored an average of one goal per game while conceding 1.5, showing both attacking potential and defensive fragility.
Under new management, Genoa initially found stability with a short unbeaten run, but back-to-back losses against Inter and Atalanta have slowed their progress. Still, their away form offers some optimism: the Grifone are unbeaten in their last three away league matches, collecting two wins and one draw. They have also been productive on the road, scoring 11 goals — a tally bettered by only three other teams in Serie A at this stage.
In terms of personnel, Genoa face several absences. Goalkeeper Leali is suspended, while Benjamin Siegrist is injured, meaning Daniele Sommariva will start in goal. The injury list also includes Junior Messias, Morten Thorsby, Hugo Cuenca, Arthur Gronbaek, and Maxwel Cornet. On the positive side, Leo Ostigard has recovered from a calf issue and is expected to return to the squad.
This fixture brings an emotional subplot as Daniele De Rossi returns to the Olimpico as Genoa’s coach, facing the club where he made over 600 appearances as a player. However, sentiment aside, Roma will be determined to bounce back from recent setbacks and maintain their push for Champions League qualification. Their defensive structure and home advantage make them favorites, especially against a Genoa side that has struggled to keep clean sheets.
Historically, Roma have had the upper hand in this matchup, winning three of the last five meetings and averaging 1.4 goals scored per game. The last head-to-head ended 3-1 in January 2025, a result that underlines the Giallorossi’s superiority at home. Given the trends, a low-scoring game is likely, with Roma’s defensive discipline and Genoa’s away scoring form balancing each other out.
Roma’s ability to control possession and limit chances should be decisive. Even a single goal could be enough to secure three points, extending their remarkable streak without a draw and spoiling De Rossi’s return to the capital.
Roma vs Genoa prediction by BetMines:
Home Win (1) with 60% probability.
This section provides average statistics and percentages on the main markets for the last 10 matches of both teams
Roma
Genoa
Under
Over
Under
Over
0.5
0
10
2
8
1.5
1
9
2
8
2.5
4
6
6
4
3.5
6
4
10
0
4.5
7
3
10
0