Sassuolo host Lazio on Tuesday, October 27, at 17:30 local time in the opening match of Serie A’s midweek round. The fixture brings together two contrasting starts to the season: Sassuolo are 14th after eight matches, while unbeaten Lazio lead the standings. Recent results favor the visitors, but Sassuolo have yet to lose at home. That contrast makes the match at MAPEI Stadium - Città del Tricolore a test of Lazio’s momentum and the hosts’ ability to respond to a difficult run.

Sassuolo’s Recent Form and Key Stats

Sassuolo come into the match after a 2-0 defeat to Como on October 24. They have taken just one point from their last four games and have lost their two most recent away fixtures, against Frosinone and Como, conceding six goals across those defeats. Over their last five matches, Sassuolo have recorded one win, one draw and three losses, scoring an average of 1.4 goals per game while conceding 2.2.

Their Serie A record stands at two wins, two draws and four defeats. An average of 2.0 goals conceded per league match underlines the defensive challenge facing Alberto Aquilani’s side, who have not kept a clean sheet this season. Sassuolo have scored 1.5 goals per game in the league, however, and the results at home offer a different perspective from their recent away defeats.

Sassuolo remain unbeaten at home this season, having beaten Bologna and Juventus and drawn with Milan. That record gives them a basis for confidence as they look to end their winless run. Their matches have also consistently featured goals: there have been more than 1.5 total goals in each of their last 10 games, while their last 12 Serie A matches have all featured at least one goal after half-time.

Lazio’s Recent Form and Key Stats

Lazio arrive after beating Parma 2-1 on October 24, a result that extended their winning sequence to four matches. Gennaro Gattuso’s team have opened the Serie A season with seven wins and one draw. Across their last five matches, they have won four and drawn one, averaging 2.6 goals scored and 1.0 conceded per game.

Their season averages provide another measure of that strong start: Lazio have scored 2.0 goals per Serie A match and conceded only 0.6. They have allowed goals in just two of their last four victories, combining productive attacking displays with a much lower overall concession rate than Sassuolo. The visitors have also taken maximum points from their away league matches so far, giving them a chance to maintain that record in this fixture.

Lazio’s longer away trends suggest that their strong results do not necessarily come with high-scoring games. Their last 13 away matches have each finished with fewer than 3.5 total goals, as have their last 11 away fixtures in Serie A. There have also been fewer than 1.5 total first-half goals in each of their last 19 away games. Those figures sit alongside their current attacking form and may be relevant to how the contest develops.

Sassuolo vs Lazio Match Analysis

Lazio have the stronger league record and arrive in better recent form, but Sassuolo’s unbeaten home start complicates the comparison. The hosts’ wins over Bologna and Juventus, followed by their draw with Milan, show why their recent away losses do not tell the whole story. For Sassuolo, the immediate task is to make that home form count while improving on a run in which they have repeatedly conceded.

The head-to-head summary also favors Lazio: across the five meetings covered, Sassuolo have one win, one draw and three defeats, averaging 0.6 goals scored and 1.4 conceded. The most recent meeting finished 2-1 on March 9, 2026. The sides each won once in the previous season’s meetings, with Sassuolo securing a narrow victory at home, so there is recent evidence of the hosts competing in this fixture.

Goals at both ends are a credible possibility given the supplied form. Sassuolo have not recorded a clean sheet this season and have conceded 2.2 goals per game across their last five, while Lazio are averaging 2.6 scored over the same span. Sassuolo’s unbeaten home record and league scoring average of 1.5 goals provide a counterpoint to Lazio’s strong defensive average. The visitors’ away trends point towards a measured scoreline rather than an assumption that their attacking form will produce a particularly high total.

Sassuolo vs Lazio prediction from BetMines: Both Teams To Score (Yes) with 57% probability.